Exploration of two natural inhibitors for treating COVID-19 from simple natural products: nature probably has all the Solutions
Keywords:
Coronavirus, COVID-19, docking, natural inhibitorAbstract
The plausible interactions of the two novel natural inhibitors; 2-(3,4-dihydroxy-5-methoxyphenyl)-3,5,7-trihydroxychromenylium (1) and 2-(3,4-dihydroxyphenyl)-3-hydroxy-7-methoxy-4H-chromen-4-one (2) (Figure 1) with one of the prominent Coronavirus target (Viral SARS-CoV-2 Spike Glycoprotein) which is involved with the survival of the virus was studied through the Glide (Molecular Docking) module of the Schrodinger (Maestro 9.1) software. The docking scores of both the two natural compounds were reported and a probable conclusion for pharmacotherapeutics was drawn from this exploration.
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2020-07-01
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Joseph, T. M., & Mahapatra, D. K. (2020). Exploration of two natural inhibitors for treating COVID-19 from simple natural products: nature probably has all the Solutions. Journal of Public Health and Sanitation, 1(1), 17-24. Retrieved from https://www.royalliteglobal.com/public-health/article/view/153
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