Exploration of two natural inhibitors for treating COVID-19 from simple natural products: nature probably has all the Solutions

Authors

  • Tomy Muringayil Joseph Chemical Faculty, Polymers Technology Department, Gdansk University of Technology, Gdansk 80233, Poland
  • Debarshi Kar Mahapatra Department of Pharmaceutical Chemistry, Dadasaheb Balpande College of Pharmacy, Nagpur 440037, Maharashtra, India

Keywords:

Coronavirus, COVID-19, docking, natural inhibitor

Abstract

The plausible interactions of the two novel natural inhibitors; 2-(3,4-dihydroxy-5-methoxyphenyl)-3,5,7-trihydroxychromenylium (1) and 2-(3,4-dihydroxyphenyl)-3-hydroxy-7-methoxy-4H-chromen-4-one (2) (Figure 1) with one of the prominent Coronavirus target (Viral SARS-CoV-2 Spike Glycoprotein) which is involved with the survival of the virus was studied through the Glide (Molecular Docking) module of the Schrodinger (Maestro 9.1) software. The docking scores of both the two natural compounds were reported and a probable conclusion for pharmacotherapeutics was drawn from this exploration.

Dimensions

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Published

2020-07-01

How to Cite

Joseph, T. M., & Mahapatra, D. K. (2020). Exploration of two natural inhibitors for treating COVID-19 from simple natural products: nature probably has all the Solutions. Journal of Public Health and Sanitation, 1(1), 17-24. Retrieved from https://www.royalliteglobal.com/public-health/article/view/153

Issue

Vol. 1 No. 1 (2020)

Section

Articles
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